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Related Experiment Videos

Pathology of pars planitis.

J E Pederson, K R Kenyon, W R Green

    American Journal of Ophthalmology
    |December 1, 1978
    PubMed
    Summary

    Pars planitis causes characteristic "snowbank" opacities due to fibroglial proliferation in the vitreous base. This inflammatory process affects the peripheral retina and vitreous, leading to complications like glaucoma.

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    Area of Science:

    • Ophthalmology
    • Pathology

    Background:

    • Pars planitis is an inflammatory condition of the eye.
    • Complications include secondary glaucoma and phthisis bulbi.

    Observation:

    • Histopathological study of seven eyes with pars planitis.
    • Intravitreal "snowbank" opacities observed overlying the pars plana.
    • Electron microscopy examined fibroglial tissue and preretinal membranes.

    Findings:

    • "Snowbanks" composed of fibrovascular tissue, inflammatory cells, and hyperplastic pars plana epithelium.
    • Extensive fibroglial proliferation in the vitreous base, drawing the peripheral retina anteriorly.
    • Lymphocytic infiltration of retinal veins noted, with sparing of arterioles.

    Implications:

    • The fibroglial "snowbank" may represent a shared inflammatory process in pars planitis.
    • Understanding this pathology can inform treatment strategies for pars planitis complications.
    • Further research into the role of astrocytes and collagen in fibroglial proliferation is warranted.

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