[Effect of narcotics on the thermoregulatory mechanisms in normo- and hypothermia]

Acute experiments on rats were made to study the effect of ether, chloral hydrate (400 mg/kg), sodium thiopental (60 mg/kg), sodium hydroxybutyrate (1500 mg/kg) and ethanol (3000 mg/kg) on rectal temperature under normothermia and the time of the onset of mild, moderate and deep hypothermia, which corresponds to the rectal temperature 33, 26 and 19 degrees C. The ratios of hypothermia development for the cooling stages under consideration and pair correlation coefficients were calculated and linear regression equations were derived.