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Enumeration of platelets.
American Journal of Clinical Pathology
|January 1, 1978
Summary
This study correlates peripheral smear platelet counts with direct methods. A ratio of 1 platelet per oil immersion field suggests a normal platelet range of 7-21 fields.
Area of Science:
- Hematology
- Clinical Pathology
Background:
- Accurate platelet enumeration is crucial for diagnosing and managing various hematological disorders.
- Direct counting methods provide precise platelet counts, but peripheral smear examination is a common, rapid screening tool.
Purpose of the Study:
- To establish a correlation between platelet counts obtained from peripheral blood smears and those from a direct counting method.
- To define a reliable visual estimation range for platelet counts on peripheral smears.
Main Methods:
- Peripheral blood smears were prepared and examined under oil immersion.
- Platelet counts were performed using a direct chamber counting method.
- A correlation was established by comparing the number of platelets per oil immersion field with the direct chamber count.
Main Results:
- A ratio of 1 platelet per oil immersion field corresponds to approximately 21,000 platelets per cubic millimeter by direct count.
- The normal average range of platelets observed per oil immersion field was determined to be 7-21.
Conclusions:
- Peripheral smear examination provides a practical method for estimating platelet counts.
- The established ratio and normal range facilitate rapid and reasonably accurate platelet assessment in clinical practice.