Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antigenic specificity in the E-rosette augmentation reaction.

S A Klemm, W J Halliday

    Immunology Letters
    |January 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Laparoscopic adrenalectomy.

    World journal of surgery·1996
    Same author

    PCR-SSCP analysis of the p53 gene in tumours of the adrenal gland.

    Clinical and experimental pharmacology & physiology·1996
    Same author

    PCR-SSCP analysis of the promoter region of the renin gene in patients with aldosterone-producing adenomas.

    Clinical and experimental pharmacology & physiology·1996
    Same author

    Clinical, biochemical and genetic approaches to the detection of familial hyperaldosteronism type I.

    Journal of hypertension·1995
    Same author

    Long-PCR of the ANP gene and PCR-SSCP analysis of the proximal promoter region of the ANP gene in patients with aldosterone producing adenoma.

    Biochemical and biophysical research communications·1995
    Same author

    Reduced renal extraction of atrial natriuretic peptide in primary aldosteronism.

    Hypertension (Dallas, Tex. : 1979)·1995
    Same journal

    Th1 recruitment in atopic dermatitis is due to suppression rather than amplification of Th2.

    Immunology letters·2026
    Same journal

    Interleukin-6: A Potential Link in the Pathophysiology of Restless Legs Syndrome.

    Immunology letters·2026
    Same journal

    The dendritic cell identity crisis: Why do conflicting classifications demand a consensus framework?

    Immunology letters·2026
    Same journal

    The malignancy within: what cancer teaches us about human bonds.

    Immunology letters·2026
    Same journal

    Progranulin enhances complement component 5a-primed neutrophil activation in antineutrophil cytoplasmic antibody-associated vasculitis.

    Immunology letters·2026
    Same journal

    The newly identified role of TRIM72, an E3 ligase, in NINJ1-mediated plasma membrane rupture: focus on its anti-inflammatory function.

    Immunology letters·2026
    See all related articles

    Murine T-lymphocytes

    Area of Science:

    • Immunology
    • Cellular immunology

    Background:

    • T-lymphocytes mediate immune responses through antigen recognition.
    • Lymphokines are signaling molecules produced by lymphocytes.

    Purpose of the Study:

    • To investigate the specificity of E-rosette augmentation (ERA) using murine T-lymphocytes.
    • To explore the dose-dependent antigen reactivity of T-lymphocytes.

    Main Methods:

    • Immunizing mice with proteins or contact-sensitizers.
    • Assessing T-lymphocyte reactivity via E-rosette augmentation (ERA).
    • Analyzing antigen dose-response curves and specificity.

    Main Results:

    • ERA exhibited bell-shaped antigen dose-response curves.
    • Optimal ERA was antigen-specific, with inhibition at moderate antigen excess.

    Related Experiment Videos

  • High antigen excess led to non-specific suppression, potentially due to antigen presentation.

    • Conclusions:

    • T-lymphocyte reactivity is antigen-specific and sensitive to antigen concentration.
    • Moderate antigen excess specifically suppresses T-cell responses.
    • This phenomenon offers a method for analyzing complex antigens.