[Clinicopathologic study in children of a diabetic mother. Review of 16 cases]

16 cases of infants of diabetic mothers were analyzed; 10 of them were live-born and died shortly afterwards; the other 6 were born dead. Among the live-born there was a high frequency of respiratory illnesses, neonatal jaundice and hemorrhagic tendency more often in lungs and C.N.S. At the necropsy, together with the findings atributtable to the mentioned illnesses there was also hyperplasia of the pancreatic islands in 100%, a high tendency to the visceral gigantism, specially in the liver, heart and lesser in the brain. And 20% had congenital malformations, chiefly in the C.N.S. genitourinary and lymphohematopoietic system. The descriptions are accompanied by a brief review of the literature.