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Regulation of poly(ADP-ribose) transferase activity by 2',5'-oligoadenylates

A D Pivazian, H Suzuki, A A Vartanian

    Biochemistry International
    |August 1, 1984
    PubMed
    Summary

    Oligoadenylates, like pppA2'pA2'pA, inhibit poly (ADP-ribose) transferase (ADPRT) activity. This inhibition may explain the antiviral and antiproliferative effects of interferon.

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