Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Can physical exercise induce an effective fibrinolysis?

B Dufaux, U Order, W Hollmann

    Thrombosis Research
    |October 1, 1984
    PubMed
    Summary

    Intense exercise causes a modest increase in fibrin(ogen) degradation products (FDP/fdp). Physical training minimally affects this response, suggesting daily exercise

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effect of Carbohydrates and Caffeine on Plasma Amino Acids, Neuroendocrine Responses and Performance in Tennis.

    Nutritional neuroscience·2016
    Same author

    Echocardiographic and biochemical analysis of cardiac function and injury among female amateur runners post-marathon.

    Wiener klinische Wochenschrift·2015
    Same author

    The spirografic oxygen deficit: its role in cardiopulmonary exercise testing.

    International journal of sports medicine·2013
    Same author

    Influences of exercise and training on the circulating concentration of prolactin in humans.

    Journal of neuroendocrinology·2011
    Same author

    pH buffering does not influence BDNF responses to exercise.

    International journal of sports medicine·2011
    Same author

    Effect of resistance exercise on serum levels of growth factors in humans.

    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2010

    Area of Science:

    • Exercise Physiology
    • Hemostasis and Thrombosis

    Background:

    • Fibrin(ogen) degradation products (FDP/fdp) are markers of fibrinolysis.
    • The impact of exercise intensity and duration on FDP/fdp levels is not fully understood.
    • Age and training status may influence FDP/fdp response to exercise.

    Purpose of the Study:

    • To investigate FDP/fdp and fragment D levels after short and prolonged exercise.
    • To examine the effects of physical training on exercise-induced FDP/fdp response.
    • To compare responses in young and elderly subjects.

    Main Methods:

    • Serum FDP/fdp and fragment D measured after graded maximal treadmill tests and prolonged running.
    • Enzyme immunoassay used for fragment D quantification.
    • Plasma fibrinogen levels assessed before and after training programs.

    Main Results:

    • Short maximal exercise did not increase FDP/fdp in elderly subjects.
    • Prolonged exercise (3h running) led to modest FDP/fdp and significant fragment D elevation.
    • Physical training slightly enhanced post-exercise FDP/fdp and fragment D, but reduced fibrinogen elevation.

    Conclusions:

    • Intense and prolonged exercise induce a modest increase in FDP/fdp.
    • Physical training has a minimal effect on the acute FDP/fdp response to exercise.
    • Daily exercise-induced fibrinolytic activation may be more relevant for thrombotic risk than resting levels.

    Related Experiment Videos