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A simple force transducer flow meter system suitable for the Langendorff heart preparation
Journal of Pharmacological Methods
|June 1, 1984
Summary
This study introduces a simple, cost-effective flow meter for Langendorff heart preparations, ensuring constant perfusion pressure and compatible signals. The device offers accurate average flow rate measurements without complex electronics, proving reliable and easy to use.
Area of Science:
- Physiology
- Biomedical Engineering
- Cardiovascular Research
Background:
- Accurate perfusion monitoring is crucial for isolated organ preparations like the Langendorff heart.
- Existing flow meters can be complex, expensive, or susceptible to experimental artifacts such as retrograde flow.
Purpose of the Study:
- To describe the construction and functionality of a novel, simple flow meter for physiological preparations.
- To provide a cost-effective and user-friendly alternative to existing commercial flow meters.
Main Methods:
- Construction of a basic flow meter utilizing simple electronic components.
- Integration with Ormed recording equipment for signal compatibility.
- Design considerations to prevent back pressure and retrograde flow effects.
Main Results:
- The developed flow meter enables constant pressure perfusion.
- Average flow rate is determined over 30-second intervals using basic electronics.
- The device demonstrates no susceptibility to retrograde flow and produces no back pressure.
Conclusions:
- The simple flow meter is adequate for applications like the Langendorff heart preparation.
- It offers a reliable, low-component-count solution for monitoring perfusion flow.
- A two-channel system variant is also detailed, further simplifying experimental setups.