Adrenoleukodystrophy. Report of two cases with relapsing and remitting courses

Two boys with adrenoleukodystrophy (ALD) had unusual clinical courses. The first had three episodes of relapse and two remissions associated with elevation and fall in CSF protein levels. The second boy has had a prolonged remission of his neurologic symptoms with continuing adrenocortical failure. There may be a limited role for steroids in the treatment of the cerebral aspects of ALD.