Multiple myeloma with bilateral orbital infiltration and polyneuropathy

Area of Science:

• Ophthalmology
• Oncology
• Hematology

Background:

• Multiple myeloma can rarely involve the orbit.
• Orbital myeloma typically presents as unilateral proptosis without pain.

Observation:

• A woman presented with bilateral orbital infiltration without proptosis.
• She experienced diplopia followed by blindness within three months.
• Her blindness resulted from visual field obstruction due to eyelids covering the corneas.

Findings:

• This is the first reported case of orbital myeloma in Australia.
• It is only the second reported case globally of bilateral primary orbital infiltration with myelomatosis.
• The underlying ocular structures remained normal despite vision loss.

Implications:

• This case expands the known clinical presentations of orbital myeloma.
• It underscores the importance of considering myeloma in atypical orbital presentations.
• Further research into early detection and management of orbital myeloma is warranted.