Radiation therapy of glottic carcinoma stage I

A detailed retrospective analysis of 81 patients with a diagnosis of glottic carcinoma stage I (T1N0M0) from 1953 to 1975 has been done. Eighty-eight per cent of the patients were male and 80 per cent of the total number were white. The majority of the patients received a dose of 64 Gy in 6 1/2 weeks. The crude 5-year actuarial survival rate was 69 per cent and the adjusted 5-year actuarial survival rate was 86 per cent. Local recurrence occurred in 12 per cent and of these 80 per cent were cured by surgery. The median time of recurrence was 25.5 months. No case of laryngeal necrosis occurred, and 10 second malignant tumors were diagnosed in the follow-up.