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Villonodular synovitis: pigmented and nonpigmented variations.

W E Miller

    Southern Medical Journal
    |September 1, 1982
    PubMed
    Summary
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    Pigmented villonodular synovitis (PVNS) is an inflammatory joint condition. Subtotal synovial resection is an effective treatment, with rare recurrences observed in this study.

    Area of Science:

    • Orthopedics
    • Pathology
    • Rheumatology

    Background:

    • Pigmented villonodular synovitis (PVNS) is a rare, benign neoplastic proliferation of the synovium.
    • Distinguishing PVNS from other soft tissue tumors, such as fibrous histiocytoma, can be challenging based on pathology alone.

    Purpose of the Study:

    • To review the clinical presentation, treatment, and outcomes of pigmented villonodular synovitis (PVNS) cases.
    • To evaluate the efficacy of subtotal synovial resection as a treatment for PVNS.

    Main Methods:

    • Retrospective review of 34 cases of PVNS diagnosed and treated at Jackson Memorial Hospital, University of Miami Medical Center over 20 years.
    • Analysis of joint involvement, treatment modalities, and recurrence rates following surgical intervention.

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    Main Results:

    • The knee (18 cases) and hip (8 cases) were the most commonly affected joints.
    • Subtotal synovial resection was the primary treatment, with no recurrences reported in the 34 cases.
    • Joint replacement was necessary in some hip cases due to acetabular involvement.

    Conclusions:

    • Subtotal synovial resection and debridement are effective treatments for PVNS, leading to rare recurrences.
    • PVNS is considered an inflammatory condition, and radiation therapy has not been utilized in its treatment at this institution.