Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Plasma testosterone in patients receiving diethylstilbestrol.

P H Beck, J W McAnich, J L Goebel

    Urology
    |February 1, 1978
    PubMed
    Summary

    Accurate plasma testosterone testing allows monitoring of prostate cancer hormonal therapy. Studies show diethylstilbestrol (DES) equally affects testosterone levels in prostate cancer patients and castrated individuals.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Time-resolved XANES speciation studies of chromium on soils during simulated contamination.

    Talanta·2008
    Same author

    Elevated prostate-specific antigen, abnormal prostate evaluation on digital rectal examination, and transrectal ultrasound and prostate biopsy.

    The Urologic clinics of North America·1999
    Same author

    Triorchidism in the sibling of a patient with recently diagnosed seminoma.

    Journal of clinical ultrasound : JCU·1995
    Same author

    Genetic susceptibility of benign prostatic hyperplasia.

    The Journal of urology·1994
    Same author

    Tubularized neourethra following radical retropubic prostatectomy.

    The Journal of urology·1993
    Same author

    Extragonadal germ cell tumor originating in iliac fossa.

    Urology·1993

    Area of Science:

    • Endocrinology
    • Oncology
    • Urology

    Background:

    • Prostate cancer treatment often involves hormonal manipulation.
    • Diethylstilbestrol (DES) is a commonly used therapeutic agent.
    • Monitoring treatment efficacy is crucial for patient management.

    Purpose of the Study:

    • To assess the efficacy of hormonal therapy in prostate cancer patients.
    • To monitor plasma testosterone levels during diethylstilbestrol (DES) treatment.
    • To establish the impact of DES on testosterone in different patient groups.

    Main Methods:

    • Plasma testosterone levels were monitored in patients with adenocarcinoma of the prostate.
    • Patients received diethylstilbestrol (DES) at a dosage of 1 mg per day.
    • Comparative analysis was performed between treated prostate cancer patients and castrated patients.

    Main Results:

    • No statistically significant difference in mean plasma testosterone was observed.
    • Testosterone levels were comparable between prostate cancer patients and castrated patients on DES.
    • The efficacy of DES in suppressing testosterone was consistent across groups.

    Conclusions:

    • Plasma testosterone assays are valuable tools for monitoring hormonal therapy in prostate cancer.
    • Diethylstilbestrol (DES) effectively suppresses testosterone levels, regardless of patient castration status.
    • Close monitoring of plasma testosterone is recommended for patients undergoing hormonal therapy for prostate cancer.

    Related Experiment Videos