Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Reduced ciliary action in chronic sinusitis.

Y Ohashi, Y Nakai

Acta Oto-Laryngologica. Supplementum

|January 1, 1983

Summary

This summary is machine-generated.

Chronic sinusitis impairs mucociliary transport due to reduced ciliary beating frequency. This study quantifies the decreased beat rate in sinusitis patients, revealing distinct ciliary action patterns.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ultrastructural studies of medullary synaptic inputs to vasopressin-immunoreactive neurons in the supraoptic nucleus of the rat hypothalamus.

Neuroscience letters·1992

Same author

TRH regulation of tracheal tension through vagal preganglionic motoneurons.

Brain research bulletin·1992

Same author

Microvasculature of normal and hydropic labyrinth.

Scanning microscopy·1992

Same author

Pathogenic factors responsible for glucose intolerance in patients with NIDDM.

Diabetes·1992

Same author

GABAergic innervation of serotonergic neurons in the dorsal raphe nucleus of the rat studied by electron microscopy double immunostaining.

Brain research bulletin·1992

Same author

Pulsatile umbilical venous flow and its clinical significance.

British journal of obstetrics and gynaecology·1992

Same journal

Towards a consensus on a hearing preservation classification system.

Acta oto-laryngologica. Supplementum·2013

Same journal

Inner ear drug delivery system from the clinical point of view.

Acta oto-laryngologica. Supplementum·2010

Same journal

Hydrogen protects vestibular hair cells from free radicals.

Acta oto-laryngologica. Supplementum·2010

Same journal

Distribution of bone marrow-derived cells in the vestibular end organs and the endolymphatic sac.

Acta oto-laryngologica. Supplementum·2010

Same journal

Impacts and limitations of medialization thyroplasty on swallowing function of patients with unilateral vocal fold paralysis.

Acta oto-laryngologica. Supplementum·2010

Same journal

A tissue-engineering approach for stenosis of the trachea and/or cricoid.

Acta oto-laryngologica. Supplementum·2010

See all related articles

Area of Science:

Otorhinolaryngology
Cellular Physiology

Background:

Mucociliary transport is crucial for clearing the respiratory tract.
Disturbances in mucociliary function are implicated in chronic sinusitis pathology.

Purpose of the Study:

To investigate the role of ciliary beating frequency in chronic sinusitis.
To characterize the patterns of ciliary action in chronic sinusitis patients.

Main Methods:

Photo-electric method used to assess mucociliary transport.
In vitro experiments on mucous membrane samples from 10 chronic sinusitis cases.
Ciliary beating frequency measured at 30 degrees C.

Main Results:

Ciliary beating frequency in chronic sinusitis was significantly reduced (409 +/- 84 beats/min at 30°C) compared to active phase (approx. 720 beats/min).

Related Experiment Videos

Mucociliary transport is impaired by both altered secretory function and decreased ciliary beating.

Three distinct ciliary action types were identified: gathering, bifocal, and scattering.

Conclusions:

Reduced ciliary beating frequency is a key factor in the mucociliary dysfunction of chronic sinusitis.
Understanding these ciliary action patterns may offer insights into disease mechanisms and potential therapeutic targets.