Oligodeoxynucleotides containing 7-deazaadenine: synthesis and recognition by restriction endonucleases

Deoxydecanucleotides containing a recognition sequence of Bg1 II and Sau 3AI, and their 7-deazaadenine analogs were synthesized by the phosphotriester method. The decanucleotides containing 7-deazaadenine in place of adenine were partially or strongly resistant to the hydrolysis by these restriction endonucleases.