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Vitamin D, rickets, and osteomalacia.

S H Doppelt

    The Orthopedic Clinics of North America
    |October 1, 1984
    PubMed
    Summary

    Rickets and osteomalacia are bone diseases with distinct features, often treatable with targeted metabolic therapy. Early orthopedic recognition aids diagnosis and management of skeletal issues.

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    Area of Science:

    • Endocrinology
    • Metabolic Bone Disease
    • Orthopedics

    Background:

    • Rickets and osteomalacia present with characteristic clinical features despite diverse underlying causes.
    • These conditions stem from various inherited and acquired metabolic abnormalities.
    • Effective management often involves addressing the specific metabolic defect.

    Purpose of the Study:

    • To discuss vitamin D metabolism.
    • To detail the clinical presentation, diagnosis, evaluation, and treatment of rickets and osteomalacia.
    • To emphasize the role of orthopedic surgeons in recognizing and managing these bone disorders.

    Main Methods:

    • Review of vitamin D metabolism.
    • Description of clinical manifestations.
    • Outline of diagnostic and therapeutic strategies.
    • Emphasis on orthopedic surgical considerations.

    Main Results:

    • Rickets and osteomalacia share stereotypical features.
    • Therapy targeting the underlying metabolic abnormality can cure or improve bone disease.
    • Orthopedic surgeons' awareness is crucial for diagnosis and managing skeletal complications.

    Conclusions:

    • Rickets and osteomalacia are treatable metabolic bone diseases.
    • Early diagnosis and management by orthopedic surgeons are vital for optimal patient outcomes.
    • Understanding vitamin D metabolism is key to managing these conditions.

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