Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Interference in immunoassay.

E L Nickoloff

    Critical Reviews in Clinical Laboratory Sciences
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Immunoassays in clinical labs can be affected by various interfering factors. This review covers common interferences from tube types, serum, and assay labels to improve diagnostic accuracy.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Patient radiation exposure during diagnostic and therapeutic interventional neuroradiology procedures.

    Journal of neurointerventional surgery·2011
    Same author

    A comparative study of thoracic radiation doses from 64-slice cardiac CT.

    The British journal of radiology·2007
    Same author

    Comparison of computed radiography and film/screen combination using a contrast-detail phantom.

    Journal of applied clinical medical physics·2003
    Same author

    Radiation doses during CT fluoroscopy.

    Health physics·2000
    Same author

    Proposition: a pregnant resident physician should be excused from training rotations such as angiography and nuclear medicine because of the potential exposure of the fetus.

    Medical physics·2000
    Same author

    CT scans through metal scanning technique versus hardware composition.

    Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society·1994
    Same journal

    Indirect methods for the verification of reference intervals in laboratory medicine.

    Critical reviews in clinical laboratory sciences·2026
    Same journal

    Sustainability and waste reduction in clinical laboratories.

    Critical reviews in clinical laboratory sciences·2026
    Same journal

    Aptamer-based biosensing strategies for influenza virus detection: a systematic and critical review of electrochemical and optical platforms.

    Critical reviews in clinical laboratory sciences·2026
    Same journal

    Advancing patient safety through laboratory quality indicators in clinical pathology.

    Critical reviews in clinical laboratory sciences·2026
    Same journal

    Blood biomarkers for the diagnosis of chorioamnionitis following preterm premature rupture of membranes: a systematic review and meta-analysis of studies since 2020.

    Critical reviews in clinical laboratory sciences·2026
    Same journal

    Single cell mechanodeformation signatures as early biomarkers for hematological malignancies.

    Critical reviews in clinical laboratory sciences·2026
    See all related articles

    Area of Science:

    • Clinical Chemistry
    • Laboratory Medicine
    • Analytical Biochemistry

    Background:

    • Immunoassays are widely used in clinical diagnostics.
    • Numerous factors can interfere with immunoassay accuracy.
    • Understanding these interferences is crucial for reliable results.

    Purpose of the Study:

    • To survey common interfering substances affecting immunoassays.
    • To categorize interferences based on their source (e.g., tube type, serum, label).
    • To inform laboratory professionals about potential assay limitations.

    Main Methods:

    • Literature review of known immunoassay interferences.
    • Categorization of interferences based on the abstract's described factors.
    • Discussion of specific examples of interfering substances.

    Related Experiment Videos

    Main Results:

    • Exogenous radioactivity interferes specifically with radioimmunoassays.
    • Other interferences affect various immunoassay types to different extents.
    • Common interfering factors include tube types, serum components, and assay labels.

    Conclusions:

    • Awareness of potential interferences is essential for accurate immunoassay interpretation.
    • Different immunoassay platforms may exhibit varying susceptibility to interference.
    • Further research may be needed to mitigate specific interference challenges.