The superior colliculus and visual neglect in rat and hamster. II. Possible mechanisms

The observations that removal of the superior colliculus in rats and hamsters produces a striking visual neglect, whereas damage to striate cortex does not, require explanation in terms of the anatomy and physiology of visual pathways in these animals. One proposal is that neglect is produced because the superior colliculus is the only visual structure directly concerned with the production of orienting movements. However, recent behavioural evidence indicates that this mechanism on its own is insufficient: collicular neglect is not confined to orienting movements, but is in part an inability to register particular kinds of visual stimulus. Two additional mechanisms are considered. The superior colliculus receives visual information that the geniculostriate pathway does not. A variety of anatomical and electrophysiological evidence suggests that this is the case. Although the exact nature of the information is unclear, there is some suggestion that the superior colliculus has a stronger representation of the peripheral field than the geniculostriate pathway, and may be more concerned with small transient stimuli throughout the visual field. An intact superior colliculus is essential for normal functioning of the geniculostriate system. Anatomical evidence indicates that there are pathways whereby: (a) visual cortex could use the superior colliculus as an output station; and (b) the superior colliculus could control signals entering or leaving the geniculostriate system, although the nature of the information carried by the pathways is not yet understood. The precise contribution of these two additional mechanisms to collicular neglect remains to be determined. However, it may be conjectured that the first would underly the deficit in stimulus detection that appears to be one component of collicular neglect, whereas the second mechanism might underly an attentional component.