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[Systemic acyclovir therapy in recurrent keratouveitis caused by herpes simplex virus]
Klinische Monatsblatter Fur Augenheilkunde
|December 1, 1984
Summary
High-dose intravenous Acyclovir effectively treated herpetic (herpes simplex virus) keratouveitis in two patients. Inflammation resolved within seven days of this potent antiviral therapy.
Area of Science:
- Ophthalmology
- Virology
- Pharmacology
Background:
- Herpetic keratouveitis, an ocular inflammation caused by herpes simplex virus, can lead to vision impairment.
- Intravenous Acyclovir is a potent antiviral medication used for severe herpes simplex virus infections.
Observation:
- Two cases of herpetic keratouveitis were treated with high-dosage intravenous Acyclovir.
- The treatment regimen involved 3 X 15 mg/kg/day of Acyclovir administered intravenously.
Findings:
- Complete resolution of ocular inflammation was observed in both patients.
- Inflammation subsided within a 7-day treatment period.
Implications:
- High-dose intravenous Acyclovir is a viable and effective treatment for severe herpetic keratouveitis.
- Prompt treatment can prevent long-term visual complications associated with herpetic eye disease.