Related Experiment Video
Updated: Aug 10, 2026

Assessment of Dopaminergic Homeostasis in Mice by Use of High-performance Liquid Chromatography Analysis and Synaptosomal Dopamine Uptake
Published on: September 21, 2017
[Test with 0.1g L-DOPA in clinical neuroses and neurosis-like states]
Abstract:
Effect of a test with administration of 0.1 g L-DOPA, reflecting the synthetic processes in sympathoadrenal system and its reactivity, on dynamics of catecholamine and DOPA excretion with urine was studied in patients with neuroses and neurosis-like states, namely, in women with climacteric syndrome, in men with sexual deteriorations, in patients with general neuroses and in patients with initial manifestations of brain circulation insufficiency. Evaluation of various specific types of sympathoadrenal system responses to the L-DOPA administration as compared with healthy persons as well as evaluation of the response types characteristic for individual syndromes, improved the diagnostics of neuroses. The test with 0.1 g DOPA permitted also to estimate the efficiency of treatment as well as to design the most specialized treatment of the patients.
More Related Videos
07:02A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
Published on: February 11, 2019
06:45Rating L-DOPA-Induced Dyskinesias in the Unilaterally 6-OHDA-Lesioned Rat Model of Parkinson's Disease
Published on: October 4, 2021