Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Physiologic requirements to perform work.

L E Farhi

    The American Review of Respiratory Disease
    |February 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Exercising muscles need adequate blood flow and composition, regulated by the circulatory and respiratory systems. Peripheral systems typically fail before the central circulation or lungs during exertion.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Revised one-step method for determination of cardiac output.

    Respiratory physiology & neurobiology·2004
    Same author

    Cardiac output: a view from Buffalo.

    European journal of applied physiology·2003
    Same author

    Cardiovascular response to submaximal exercise in sustained microgravity.

    Journal of applied physiology (Bethesda, Md. : 1985)·1996
    Same author

    Cardiorespiratory response to lower body negative pressure.

    Aviation, space, and environmental medicine·1994
    Same author

    Local pulmonary blood flow: control and gas exchange.

    Respiration physiology·1993
    Same author

    Prolonged lobar hypoxia in vivo enhances the responsivity of isolated pulmonary veins to hypoxia.

    The American review of respiratory disease·1992
    Same journal

    Human lung lysozyme: sources and properties.

    The American review of respiratory disease·2015
    Same journal

    "Immotile-cilia" syndrome and ciliary abnormalities induced by infection and injury.

    The American review of respiratory disease·2013
    Same journal

    Adult criteria for obstructive apnea do not identify children with serious obstruction.

    The American review of respiratory disease·1993
    Same journal

    Cell adhesion molecules and the bronchial epithelium.

    The American review of respiratory disease·1993
    Same journal

    Adhesion molecules and cytokine production.

    The American review of respiratory disease·1993
    Same journal

    Molecular mechanisms mediating lymphocyte recirculation, inflammation, and metastasis formation.

    The American review of respiratory disease·1993
    See all related articles

    Area of Science:

    • Physiology
    • Exercise Physiology
    • Cardiovascular and Respiratory Systems

    Background:

    • Exercising muscles require continuous blood supply with optimal oxygen and carbon dioxide levels.
    • The body employs complex circulatory and respiratory adjustments to meet the metabolic demands of exercise.
    • Organ function may be temporarily compromised to prioritize exercising muscle needs.

    Purpose of the Study:

    • To elucidate the physiological mechanisms supporting exercising muscle.
    • To understand the interplay between central and peripheral systems during physical exertion.
    • To identify the primary sites of functional limitation during exercise.

    Main Methods:

    • The study is a physiological review and analysis of existing data.
    • It examines the roles of the circulatory system (cardiac output, blood flow distribution) and respiratory system (alveolar ventilation).

    Related Experiment Videos

  • It analyzes the body's hierarchical response to exercise demands, including potential organ "sacrifice".

    • Main Results:

    • The circulatory system increases cardiac output and redirects blood flow, while the lungs maintain blood gas homeostasis.
    • A functional hierarchy prioritizes exercising muscles, leading to temporary depression of other organ functions.
    • In healthy individuals, the peripheral systems fail before the central circulation or lungs, as evidenced by increased blood pressure and anaerobic metabolism during maximal exertion.

    Conclusions:

    • The heart and lungs adequately support exercising muscles in healthy individuals.
    • Functional limitations during exertion typically arise from peripheral factors, not central cardiovascular or respiratory failure.
    • Impaired functional capacity during exertion in patients often indicates limitations within their central circulation or respiratory system.