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Nootropic drugs reduce immobility in behavioural despair test in mice
Biomedica Biochimica Acta
|January 1, 1984
Abstract:
The effect of different nootropic drugs (piracetam, pyritinol, meclofenoxate, methylglucamine orotate, dihydroergotoxine, nicergoline, vinpocetine) on the duration of immobility in the behavioural despair test in mice was studied. All tested nootropics exhibited a dose-related reduction in immobility. In connection with the discussed role of monoaminergic processes in the state of immobility our data support the possible participation of central monoaminergic systems in the mechanisms of action of nootropic drugs.