[Clinical application of eperisone hydrochloride to neurogenic bladder]

Eperisone hydrochloride, a striated muscle relaxant, was tried on 20 patients suffering from neurogenic bladder due to various reasons. Clinical effectiveness was evaluated by subjective symptoms, residual urine, cystometry and electromyography of the external urethral sphincter. Difficulty of urination was improved in 9 of the 20 patients. Decrease of residual urine by more than 40% was seen in 10% of the 20 patients. No significant changes were observed in the cystometrograms. On the electromyograph, external sphincter spasms were seen in 6 of the 8 patients, and partially improved in 2 patients. No marked side effects were observed.