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Halo nevi and melanoma
American Family Physician
|August 1, 1984
Summary
Halo nevi, or nevi with surrounding depigmentation, may indicate hidden melanoma. Biopsy single halo nevi and perform full skin and eye exams to rule out melanoma.
Area of Science:
- Dermatology
- Oncology
- Immunology
Background:
- Halo nevi are benign-appearing melanocytic nevi characterized by a surrounding depigmented halo.
- The association between halo nevi and melanoma, while not fully understood, warrants clinical vigilance.
Observation:
- A single halo nevus can be a sign of occult melanoma or melanoma in a distant site.
- Patients presenting with halo nevi require comprehensive dermatological and ophthalmological evaluation.
Findings:
- Biopsy of a solitary halo nevus is recommended to exclude melanoma.
- Systemic examination for melanoma, including skin and ocular assessments, is crucial in patients with halo nevi.
Implications:
- Early detection of melanoma associated with halo nevi can improve patient outcomes.
- Further research into the immunologic mechanisms linking halo nevi and melanoma is needed.