[Study of conformation-dependent isotherms of DNA hydration]

By the method of gravimetry and piezomicrobalance native and denaturated DNA hydration isotherms are obtained. Their adsorptional ability difference observed is interpreted according to IR-data, which show that if sugar-phosphate skeleton hydration levels are similar for these conformations, their nitrous base hydration is strongly different. BET-fitting of isotherms obtained discovered significant water binding energy heterogeneity of native DNA hydration-active sites.