[Unithiol in the treatment of secondary amyloidosis patients]

Seventy-five patients with secondary amyloidosis were treated with unithiol. Good objective results were obtained in 19 patients, who demonstrated considerable improvement of the general well-being, reduction in proteinuria, edemas, appreciable elevation of the levels of total protein. albumins and sulfhydryl groups in blood serum. Satisfactory results were obtained in 18 patients who showed a certain improvement of the general well-being, moderate drop of proteinuria, elevation of the levels of albumins and sulfhydryl groups in blood serum. Twenty-four patients noted only subjective improvement. Fourteen patients did not respond or showed deterioration of the health status. Three patients developed allergic rash which disappeared after drug discontinuation and administration of the common desensitization agents.