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Related Experiment Videos

[Necrotic funisitis].

S Sarrut, M Vodovar

    Revue Francaise De Gynecologie Et D'Obstetrique
    |July 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    This study details funisitis with Wharton's jelly necrosis, often leading to premature birth. Newborns may show hyperleukocytosis and high IgM, but typically recover well without infection signs.

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    Area of Science:

    • Pathology
    • Neonatology
    • Obstetrics

    Context:

    • Presents a specific type of funisitis characterized by perivascular necrosis of Wharton's jelly.
    • Highlights minimal accompanying leukocyte reaction and variable placental inflammatory lesions.
    • Notes that cord necrosis is macroscopically visible.

    Purpose:

    • To describe the clinical and pathological features of this specific funisitis.
    • To investigate the neonatal outcomes and laboratory findings associated with this condition.
    • To explore potential etiologies, including infectious and non-infectious causes.

    Summary:

    • Eighty-eight cases of funisitis with perivascular Wharton's jelly necrosis are reported.
    • Affected neonates are often premature, with hyperleukocytosis and elevated cord blood IgM at birth, despite rare clinical signs of infection.

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  • Immediate survival and postnatal development are generally favorable, with spontaneous resolution of hyperleukocytosis.

    • Impact:

    • Provides a detailed characterization of a distinct placental pathology.
    • Informs clinical management and understanding of neonatal adaptation in affected infants.
    • Highlights the need for further research into the etiology of this condition, differentiating it from typical infections.