The pathology of pingueculae in Gaucher's disease

Several reports have noted an apparent association between pingueculae and Gaucher's disease and suggested that the yellow coloring of these lesions is attributable to Gaucher cells. The authors biopsied pingueculae from ten patients with this disorder and examined them by serial light microscopy and electron microscopy. They failed to find Gaucher cells in any specimen, but, as typical for pingueculae, the elastosis observed histologically could account for their yellow hue.