Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Congenital anterior segment epithelialisation (case).

L W Hirst

    Australian Journal of Ophthalmology
    |August 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Posterior polymorphous endothelial dystrophy and iridocorneal endothelial syndrome may share a common cause: congenital abnormal cell growth on the posterior cornea during development. This suggests a unified understanding of these distinct corneal endothelial diseases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Intraorbital anatomy of the koala (Phascolarctos cinereus).

    The Anatomical record·2002
    Same author

    Bony orbital anatomy of the koala (Phascolarctos cinereus).

    The Anatomical record·2002
    Same author

    Corneal endothelial response to induced myopia in the chicken.

    Clinical & experimental ophthalmology·2001
    Same author

    Impression cytology in the diagnosis of ocular surface squamous neoplasia.

    The British journal of ophthalmology·2001
    Same author

    The cytomorphology of ocular surface squamous neoplasia by using impression cytology.

    Cancer·2001
    Same author

    Use of topical cyclosporin for conjunctival manifestations of actinic prurigo.

    American journal of ophthalmology·2000
    Same journal

    The use of extended wear contact lenses in aphakia.

    Australian journal of ophthalmology·1984
    Same journal

    Closed microsurgery in trauma.

    Australian journal of ophthalmology·1984
    Same journal

    Fine needle aspiration biopsy of orbital lesions using CT scan control.

    Australian journal of ophthalmology·1984
    Same journal

    Macular electroretinograms: their accuracy, specificity and implementation for clinical use.

    Australian journal of ophthalmology·1984
    Same journal

    Solitary silent venous papillary loops and ocular hypertension.

    Australian journal of ophthalmology·1984
    Same journal

    Repositioning of Descemet's membrane: a case report.

    Australian journal of ophthalmology·1984
    See all related articles

    Area of Science:

    • Ophthalmology
    • Corneal Diseases
    • Developmental Biology

    Background:

    • Posterior polymorphous endothelial dystrophy (PPED) and iridocorneal endothelial syndrome (ICES) present overlapping clinical and microscopic features.
    • Despite differing inheritance patterns and disease severity, a shared underlying pathology is suspected.

    Purpose of the Study:

    • To investigate a potential common pathogenetic mechanism for PPED and ICES.
    • To explore the developmental origins of these related corneal endothelial disorders.

    Main Methods:

    • Comparative analysis of specular microscopy findings.
    • Review of clinical course and histopathological data.
    • Embryological pathway analysis.

    Main Results:

    Related Experiment Videos

    • Shared specular microscopic findings, clinical progression, and histopathological characteristics were identified between PPED and ICES.
    • A common mechanism involving congenital epithelialization of the posterior corneal surface during embryogenesis is proposed.

    Conclusions:

    • Congenital abnormal epithelial cell migration in the anterior segment, unhindered by normal endothelium, may underlie both PPED and ICES.
    • This suggests a unified pathogenetic model for these distinct corneal endothelial dystrophies.