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[Development and fate of premature infants--then and now]

G Haas

    Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
    |October 1, 1983
    PubMed

    Insights

    Advances in technology enable survival for premature infants with very low birth weight. Historical context reveals evolving survival rates and persistent challenges in reducing serious sequelae for these vulnerable infants.

    Area of Science:

    • Neonatal care
    • Pediatric intensive care
    • Perinatal medicine

    Context:

    • Modern technology improves survival rates for very low birth weight infants.
    • Historical analysis of neonatal intensive care programs is crucial for evaluating current effectiveness.
    • Early 20th-century work by A. Ylppö laid groundwork for low birth weight infant survival.

    Purpose:

    • To provide historical perspective on the survival and outcomes of low birth weight infants.
    • To discuss the evolution of intensive care for premature infants.
    • To highlight the ongoing challenges in reducing morbidity in surviving premature infants.

    Summary:

    • Survival rates for premature infants have improved due to technological advancements.
    • Post-WWII therapeutic innovations initially worsened outcomes, but improvements in the 1960s reduced serious sequelae.
    • While mortality has decreased, the rate of severe long-term health issues in surviving premature infants has remained stable for 15 years.

    Impact:

    • Informs current discussions on the effectiveness and efficiency of neonatal intensive care.
    • Emphasizes the need for continued research and technological innovation to reduce long-term morbidity.
    • Provides a historical framework for understanding progress and persistent challenges in neonatal survival and outcomes.

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