[Effect of hyperimmunization with tick-borne encephalitis virus on lipid metabolism]

Prolonged administration to rabbits of the brain tissue of albino mice and of the cell culture of chick embryo with and without the tick-borne encephalitis virus was accompanied by the changes in the qualitative fatty acid composition in the blood serum in the direction of increase of the polyunsaturated compounds; iodine number increased in the liver. A five-cycle immunization with the virus-containing material and with the brain tissue led to the rise in the content of blood serum beta-lipoproteins. The noted deviations were more pronounced in using the tick-borne encephalitis virus. Hyperimmunization with the virus-containing antigen promoted elevation of the lipolytic activity of the blood serum and of the liver tissue.