[Chymotrypsin activity in the stool: comparison of a new photometric technic and the standard titrimetric method]

A newly developed photometric assay for determination of fecal chymotrypsin is compared with the titrimetric standard method. Correlation of both technics was highly significant with a correlation coefficient of r = 0.975. The precision of both methods is satisfactory, with a coefficient of variation of 3.7% for the photometric and 1.8% for the titrimetric method. The clinical value of fecal chymotrypsin tests and other "tubeless" function tests is discussed with special reference to diagnosis and prognosis of chronic pancreatitis.