[Experimental studies on tumor implanted into cerebrospinal fluid: with special reference to tumor growth]

The incidence of metastasis to another organs of the intracranial tumors is rare, while the intracranial dissemination of brain tumor is often experienced clinically. For this purpose of the formation and growth of the intracranial tumor dissemination, VX2 carcinomas implanted into cisterna magna of 24 New Zealand rabbits are studied by neuroradiological and pathological methods. Twenty-one out of 24 (87%) had tumors intracranially. Nineteen cases out of 24 rabbits developed intraventricular tumors selectively. Two cases without the development of tumors showed moderate dilated lateral ventricles. Thiry-seven percent of implanted tumor cases were demonstrated by 3 times magnification cerebral angiography. While CT presented 67 percent of tumors indicating about two times higher detection than magnification cerebral angiography. From the result of these experiment, the detection of tumors by CT was two times higher than the magnification angiography.