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Updated: Jul 8, 2026
08:05
Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
Occupational asthma due to poultry mites.
The Journal of Allergy and Clinical Immunology
|January 1, 1984
Summary
The northern fowl mite (NFM) is a significant cause of occupational asthma and rhinitis in poultry workers. Allergy testing confirmed NFM
Area of Science:
- Occupational Medicine
- Allergology
- Veterinary Entomology
Background:
- Poultry workers may develop respiratory issues linked to their occupation.
- The northern fowl mite (NFM) is a common parasite in poultry environments.
Purpose of the Study:
- To investigate the role of the northern fowl mite (NFM) in occupational respiratory diseases among poultry workers.
- To assess allergic sensitization to NFM in affected individuals.
Main Methods:
- Skin prick tests and radioallergosorbent tests (RAST) were used to evaluate allergic responses.
- Bronchial provocation tests were conducted with NFM extract in a sensitized individual.
Main Results:
- 10 out of 16 atopic poultry workers showed immediate reactions to NFM.
- NFM was the most reactive antigen in skin testing compared to other poultry allergens.
- Bronchial challenge demonstrated an immediate and significant decline in lung function (FEV1) upon NFM exposure.
Conclusions:
- The northern fowl mite (NFM) plays a role in occupational allergic respiratory disease in poultry farmers.
- Clinical histories, positive allergy tests, and bronchial challenges support NFM as an allergen.
- NFM sensitization is a key factor in asthma and rhinitis development in this occupational group.
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