Related Experiment Video
Updated: Jul 25, 2026

07:44
Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
Adenomyomatosis of the gallbladder
American Journal of Surgery
|February 1, 1984
Summary
Adenomyomatosis of the gallbladder, a condition causing gallbladder wall thickening, often mimics gallstones. Surgical removal (cholecystectomy) effectively resolves symptoms in most patients.
Area of Science:
- Gastroenterology
- Surgical Pathology
Background:
- Adenomyomatosis involves gallbladder mucosa hyperplasia and muscularis hypertrophy, potentially due to bile outflow obstruction.
- This leads to increased intracystic pressure and intramural diverticula formation.
Purpose of the Study:
- To evaluate the clinical presentation and surgical outcomes of patients with adenomyomatosis mimicking calculous cholecystitis.
Main Methods:
- Retrospective review of 1,500 cholecystectomies over 10 years.
- Analysis of 9 patients diagnosed with adenomyomatosis without other gallbladder pathology.
Main Results:
- These 9 patients had symptoms similar to gallstones, with a mean symptom duration of 7.7 years.
- Eight of nine patients experienced symptom resolution post-cholecystectomy; one had marked improvement.
Conclusions:
- Adenomyomatosis can present with symptoms indistinguishable from calculous cholecystitis.
- Cholecystectomy is indicated for patients with adenomyomatosis and symptoms mimicking gallstone disease.
Related Concept Videos
Gallbladder
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
Pyloric Obstruction
Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Appendicitis
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Cirrhosis I: Introduction
Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Cholecystitis
Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...

