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HLA antigens in pityriasis versicolor
Tissue Antigens
|January 1, 1984
Summary
This study investigated Human Leukocyte Antigen (HLA) antigen distribution in Pityriasis Versicolor patients. No significant differences in HLA antigen frequencies were observed between patients and healthy controls.
Area of Science:
- Immunogenetics
- Dermatology
Background:
- Pityriasis Versicolor is a superficial fungal infection of the skin.
- The role of Human Leukocyte Antigen (HLA) genes in Pityriasis Versicolor susceptibility is not well-established.
Purpose of the Study:
- To investigate the association between specific Human Leukocyte Antigen (HLA) antigen distributions and Pityriasis Versicolor.
- To determine if certain HLA alleles are more prevalent in individuals with Pityriasis Versicolor.
Main Methods:
- Case-control study design.
- Human Leukocyte Antigen (HLA) typing was performed on 48 patients diagnosed with Pityriasis Versicolor.
- HLA antigen frequencies were compared to those of 134 healthy controls.
Main Results:
- A total of 30 Human Leukocyte Antigen (HLA) antigens were analyzed.
- No statistically significant deviations in the distribution of the studied HLA antigens were found in the Pityriasis Versicolor patient group compared to the control group, even after adjusting for multiple comparisons.
Conclusions:
- The study found no significant association between the tested Human Leukocyte Antigen (HLA) antigens and Pityriasis Versicolor.
- These findings suggest that HLA antigen distribution may not play a major role in the susceptibility or pathogenesis of Pityriasis Versicolor.