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Nontuberculous mycobacteria.

C B Hartley, H Yeager

    American Family Physician
    |April 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Nontuberculous mycobacteria are frequently found in clinical cultures. While often harmless, these bacteria can cause serious infections affecting various body systems.

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    Area of Science:

    • Microbiology
    • Infectious Diseases
    • Clinical Diagnostics

    Background:

    • Nontuberculous mycobacteria (NTM) are increasingly identified in clinical microbiology laboratories.
    • Distinguishing pathogenic NTM from contaminants or colonizers is crucial for patient care.
    • NTM infections can manifest in diverse clinical presentations.

    Purpose of the Study:

    • To highlight the prevalence of Nontuberculous Mycobacteria in clinical settings.
    • To underscore the pathogenic potential of NTM beyond mere contamination.
    • To outline the spectrum of diseases caused by NTM.

    Main Methods:

    • Analysis of mycobacterial culture results from clinical laboratories.
    • Review of clinical data associated with positive NTM cultures.

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  • Categorization of NTM as contaminants, colonizers, or causative agents of disease.

    • Main Results:

    • Nontuberculous mycobacteria are detected in nearly 50% of mycobacterial cultures in the US.
    • A substantial proportion of NTM isolates are associated with significant human infections.
    • Identified NTM infections include pulmonary, soft tissue, cutaneous, lymphatic, ocular, bone, postsurgical, cardiac, and disseminated diseases.

    Conclusions:

    • Nontuberculous mycobacteria represent a significant diagnostic challenge in clinical laboratories.
    • Clinical vigilance is essential to recognize NTM as a cause of diverse infections.
    • Accurate identification and differentiation of NTM are critical for appropriate patient management.