Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Synovial osteochondromatosis and pseudogout.

C M Wise, G E Wheeler, W R Irby

    The Journal of Rheumatology
    |April 1, 1984
    PubMed
    Summary

    This study reports a rare case of recurrent knee effusions in a patient with synovial osteochondromatosis. The findings highlight the presence of calcium pyrophosphate dihydrate (CPPD) crystals without radiographic evidence of chondrocalcinosis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Modulation-transfer-function-based optical sensitivity and tolerancing programs.

    Applied optics·2010
    Same author

    Automatic data reduction of certain holographic interferograms.

    Applied optics·2010
    Same author

    More Aggressive Drug Treatment of Rheumatoid Arthritis in a University-based Practice.

    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2008
    Same author

    Effect of organizational change on the individual employee.

    The health care manager·2001
    Same author

    Methotrexate in the management of immune mediated cochleovesitibular disorders: clinical experience with 53 patients.

    The Journal of rheumatology·2001
    Same author

    Gout: diagnosis, pathogenesis, and clinical manifestations.

    Current opinion in rheumatology·2001

    Area of Science:

    • Rheumatology
    • Crystal Arthropathies
    • Orthopedic Pathology

    Background:

    • Recurrent knee effusions can indicate underlying joint pathology.
    • Synovial osteochondromatosis is a condition characterized by the formation of cartilage and bone within the joint synovium.
    • Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, often associated with chondrocalcinosis, can cause inflammatory arthritis.

    Observation:

    • A middle-aged male presented with recurrent inflammatory effusions in the right knee.
    • Radiographic imaging revealed findings consistent with synovial osteochondromatosis.
    • Polarized light and electron microscopy identified calcium pyrophosphate dihydrate (CPPD) crystals in the synovial fluid of the affected knee.

    Findings:

    • Despite the presence of CPPD crystals, radiographic evidence of chondrocalcinosis was absent in both the affected and unaffected joints.
    • Analysis of noninflammatory fluid from the contralateral knee revealed the presence of apatite crystals.
    • This case presents a unique association between CPPD crystals and synovial osteochondromatosis without concurrent chondrocalcinosis.

    Implications:

    • The findings suggest a potential, yet not fully understood, relationship between CPPD crystal deposition and synovial osteochondromatosis.
    • This case challenges the typical radiographic presentation of CPPD crystal disease by demonstrating its occurrence without chondrocalcinosis.
    • Further research is warranted to elucidate the pathogenic mechanisms linking these two distinct conditions and their clinical manifestations.

    Related Experiment Videos