[Two cases of Buschke-Löwenstein tumor]

We report two cases of Buschke-Löwenstein Tumor on 39- and 55-year-old males. Both patients presented with mass and pain of glans penis. Pathological diagnosis of biopsy specimens were condyloma acuminatum in both cases. Bleomycin was not effective. Therefore, tumor resection in the first case and partial penectomy on second case were performed. Pathological examination revealed hyperkeratosis, acanthosis and downward growth of the prickle cell layer. But cellular atypia were not seen. Pathological diagnosis was Buschke-Löwenstein tumor. Our two patients are alive with no evidence of disease after 10 years. Pathological and clinical problems of Buschke-Löwenstein tumor were discussed by review of the literature.