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Updated: Aug 21, 2026
07:42
Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Chromosomes in human large bowel tumors. A study of chromosome #1
Cancer Genetics and Cytogenetics
|August 1, 1984
Abstract:
Chromosome studies on 49 patients with large bowel adenocarcinomas showed abnormalities of chromosome #1 in 19 cases (39%). One had monosomy, 13 showed trisomy, and 5 cases had structural abnormalities. Eighteen patients had tumors on the right side of the colon; of these, only 3 had an abnormal #1 (17%); 16 of 28 tumors (57%) located on the left side had abnormalities of #1. The regions of consistent duplication of 1q were q24----q44? The presence or absence of changes of chromosome #1 may be useful as a prognostic indicator in large bowel cancer.
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