[Bullous angiolymphoid hyperplasia with eosinophilia].

Area of Science:

• Dermatology
• Pathology

Background:

• Angiolymphoid hyperplasia with eosinophilia (AHHE) is a rare condition.
• A bullous variant of AHHE is described, presenting unique clinical and histological features.

Observation:

• Two patients presented with a bullous variant of AHHE localized to the head.
• Lesions included inflammatory, infiltrated plaques with recurrent bullous eruptions.
• Prurigo-like papules were also noted on the trunk and arms.

Findings:

• Histological examination showed a characteristic pattern.
• Findings included cutaneous lymphocytic infiltrate, lymphoid follicle formation, and atypical vascular proliferation.
• Significant tissue eosinophilia and subepidermal blister formation were observed.

Implications:

• This case series expands the understanding of AHHE variants.
• Recognizing the bullous form is crucial for accurate diagnosis and management.
• Further research into the pathogenesis of bullous AHHE may be warranted.