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Diurnal variations in intraocular pressure. Chronic open angle glaucoma: preliminary report
1Albert Einstein College of Medicine/Montefiore Hospital & Medical Centre, Bronx, New York.
Abstract:
Human beings have a diurnal variation in their intraocular pressure and this variation is related to the sleep-wake cycle. Patients with chronic open angle glaucoma have a similar fluctuation in intraocular pressure and, even without medication, may achieve a "normal" intraocular pressure several hours into their sleep period. Two patients with chronic open angle glaucoma, maintained on their usual miotic therapy, also maintained a normal diurnal fluctuation in intraocular pressure as did one patient with a unilaterally transected optic nerve and another with a surgically divided trigeminal nerve.
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