Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lithium intoxication. A case study.

C L Winek, J D Bricker, F W Fochtman

    Forensic Science International
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    This study details a fatal lithium carbonate ingestion case. We analyzed lithium distribution in tissues and biological fluids to understand its toxic effects.

    Related Experiment Videos

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Drug and chemical blood-level data 2001.

    Forensic science international·2001
    Same author

    Chemical burn from alkaline batteries--a case report.

    Forensic science international·1999
    Same author

    Drowning due to cyclobenzaprine and ethanol.

    Forensic science international·1999
    Same author

    Heroin fatality due to penile injection.

    The American journal of forensic medicine and pathology·1999
    Same author

    Accidental death due to inhalation of butane.

    Journal of analytical toxicology·1997
    Same author

    Fatal inhalation of 1,1,1-trichloroethane.

    Forensic science international·1997
    Same journal

    Technical note: Development of a UHPLC-MS/MS method for the analysis of hCG and IGF-I from dried blood spots: A preliminary study.

    Forensic science international·2026
    Same journal

    A novel and robust deep learning model for sibling firearm matching.

    Forensic science international·2026
    Same journal

    Changes in C-reactive protein levels over time in high-temperature environments using postmortem blood.

    Forensic science international·2026
    Same journal

    Insights from the first synthetic cannabinoid clandestine lab dismantled in Brazil.

    Forensic science international·2026
    Same journal

    Determination of the new psychoactive substances MDMB-4en-PINACA, ADB-BUTINACA and some of their metabolites in blood and urine using DLLE-LC-MS/MS: application to real forensic case samples.

    Forensic science international·2026
    Same journal

    The revolver halo as a forensic marker: Raman spectroscopic evidence of primer-driven gunshot residue deposition.

    Forensic science international·2026
    See all related articles

    Area of Science:

    • Toxicology
    • Pharmacokinetics

    Background:

    • Lithium carbonate is a mood stabilizer with a narrow therapeutic index.
    • Overdose can lead to severe toxicity and fatality.

    Observation:

    • A case of fatal lithium carbonate ingestion is presented.
    • Detailed analysis of lithium distribution in various tissues and biological fluids was performed.

    Findings:

    • Lithium concentrations were quantified in blood, urine, liver, kidney, and brain tissues.
    • The distribution pattern provides insights into lithium's systemic effects post-ingestion.

    Implications:

    • Understanding lithium distribution is crucial for managing lithium toxicity.
    • This case highlights the importance of therapeutic drug monitoring and prompt intervention in overdose cases.