Detection and activity of blood group B gene-associated alpha-galactosyltransferase in human urine

alpha-Galactosyltransferase which participates in the biosynthesis of blood group B substance was found in urine from group B and AB healthy persons of both secretors and non-secretors. The activity of alpha-galactosyltransferase in the urine of a healthy variant Bm person was lower than that found in a normal group B person. This enzyme in urine of A1Bm persons must be much lower than that in normal AB persons. Its activity was not detected by the method of group O to group B transformation or erythrocytes.