Related Experiment Video
Updated: Aug 8, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
Signet-ring cell lymphoma
Abstract:
In a small cleaved, follicular center cell (poorly differentiated) lymphoma the majority of the cells appeared vacuolated by light microscopy. This is an example of the recently described signet-ring cell lymphoma. Immunoperoxidase staining demonstrated that the cells contained IgG/k. Ultrastructural observations indicated that small vacuoles coalesce to form the large vacuoles, which contain microvesicles approximately 50 nm in diameter.
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