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Updated: Jul 31, 2026
06:24
Minimal Erythema Dose (MED) Testing
Published on: May 28, 2013
Summary
Topical corticosteroids and lubricants showed similar effectiveness for psoriasis treatment with UV irradiation. Corticosteroids did not speed up clearing or prevent faster recurrences. More frequent UV exposure led to worse burns.
Area of Science:
- Dermatology
- Phototherapy
- Psoriasis Treatment
Background:
- Psoriasis is a chronic inflammatory skin condition.
- Topical corticosteroids and lubricants are commonly used for skin conditions.
- UV irradiation is a recognized treatment for psoriasis.
Purpose of the Study:
- To compare the efficacy of potent topical corticosteroids versus lubricating agents.
- To evaluate their use in combination with UV irradiation for psoriasis.
- To assess treatment duration, recurrence rates, and adverse effects.
Main Methods:
- A bilateral symmetrical study design involving 26 psoriasis patients.
- Comparison of topical corticosteroids and lubricants alongside UV irradiation.
- Assessment of psoriasis resolution (≥75%), treatment frequency, and recurrence.
Main Results:
- No significant difference in achieving ≥75% psoriasis resolution between corticosteroids and lubricants.
- Topical corticosteroids did not reduce the number of UV treatments needed for clearance.
- No faster recurrence rates were observed with topical corticosteroid use.
Conclusions:
- Topical corticosteroids offer no significant advantage over lubricants when combined with UV irradiation for psoriasis.
- Treatment frequency and severity of UV-induced burns may influence outcomes.
- Further research into optimal combination therapies for psoriasis is warranted.
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