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Pathophysiology of diabetes mellitus
The Medical Clinics of North America
|July 1, 1978
Summary
New methods for studying insulin binding and action in vivo are available. This research explores insulin resistance and glucagon
Area of Science:
- Endocrinology
- Metabolic Diseases
Background:
- Insulin resistance is implicated in adult-onset diabetes.
- The role of glucagon in this condition is under investigation.
Purpose of the Study:
- To explore the role of insulin resistance in adult-onset diabetes.
- To investigate the contribution of glucagon to the diabetic syndrome.
Main Methods:
- Development of techniques for examining insulin binding to target cells.
- Evaluation of in vivo insulin action.
Main Results:
- New data on glucagon's contribution to the syndrome have emerged.
- Renewed interest in insulin resistance as a factor in adult-onset diabetes.
Conclusions:
- Insulin resistance may play a significant role in adult-onset diabetes.
- Glucagon's involvement in the diabetic syndrome warrants further study.