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Visual field survival: the response to timolol therapy in open-angle glaucoma.
The British Journal of Ophthalmology
|April 1, 1983
Summary
Visual field survival measurement is a reliable indicator for tracking glaucoma progression during timolol maleate treatment. This method proved more consistent than intraocular pressure monitoring in a 3-year study.
Area of Science:
- Ophthalmology
- Clinical Medicine
- Glaucoma Research
Background:
- Chronic simple glaucoma management requires accurate methods to assess treatment efficacy.
- Intraocular pressure (IOP) is a key factor, but its correlation with visual field progression can vary.
- Timolol maleate is a common treatment for reducing IOP in glaucoma patients.
Purpose of the Study:
- To develop and evaluate a simple method for quantifying visual field survival.
- To assess the progression of chronic simple glaucoma in patients treated with timolol maleate over three years.
- To compare the efficacy of visual field survival measurement versus IOP monitoring in guiding glaucoma treatment.
Main Methods:
- A cohort of 36 patients with chronic simple glaucoma was treated with timolol maleate for three years.
- Visual field survival was quantified using a newly devised simple method.
- Intraocular pressure (IOP) was routinely monitored using tonometry.
- Goldmann field studies were conducted concurrently with IOP measurements.
Main Results:
- Timolol maleate therapy resulted in sustained IOP reductions ranging from 24.3% to 34.5%.
- Statistical analysis indicated that visual field survival measurement was a more consistent clinical guide to glaucoma progression than IOP (p < 0.001).
- Sixty-three percent of patients monitored for field survival showed no significant visual field loss during the study period.
Conclusions:
- Visual field survival quantification offers a more reliable assessment of glaucoma progression under treatment compared to IOP monitoring.
- Timolol maleate effectively reduces IOP and can preserve visual fields in a majority of treated patients.
- The study highlights the importance of visual field assessment in managing chronic simple glaucoma.
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