Related Experiment Videos
R plasmids in Corynebacterium xerosis strains
Antimicrobial Agents and Chemotherapy
|March 1, 1983
Summary
Antibiotic resistance plasmids were identified in Corynebacterium xerosis strains from otitis media patients. These plasmids confer resistance to multiple common antibiotics, including chloramphenicol, erythromycin, and tetracycline.
Area of Science:
- Microbiology
- Genetics
- Infectious Diseases
Background:
- Otitis media is a common infection.
- Antibiotic resistance is a growing public health concern.
- Plasmids are mobile genetic elements that can carry resistance genes.
Purpose of the Study:
- To investigate the presence of antibiotic resistance plasmids in Corynebacterium xerosis strains.
- To identify the specific antibiotic resistance genes carried by these plasmids.
Main Methods:
- Isolation of Corynebacterium xerosis strains from patient samples.
- Plasmid DNA extraction and characterization.
- Antimicrobial susceptibility testing.
Main Results:
- Plasmids conferring resistance to chloramphenicol, erythromycin, kanamycin, streptomycin, and tetracycline were detected.
- These resistance genes were found in Corynebacterium xerosis strains isolated from otitis media.
Conclusions:
- Corynebacterium xerosis can harbor multi-drug resistance plasmids.
- The presence of these plasmids may contribute to treatment challenges in otitis media.