Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aortic saddle embolus. A twenty-year experience.

R W Busuttil, G Keehn, J Milliken

    Annals of Surgery
    |June 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Medicine in motion: Opportunities, challenges and data analytics-based solutions for traditional medicine integration into western medical practice.

    Journal of ethnopharmacology·2020
    Same author

    Myrcene and terpene regulation of TRPV1.

    Channels (Austin, Tex.)·2019
    Same author

    Differential regulation of calcium signalling pathways by components of Piper methysticum ('Awa).

    Phytotherapy research : PTR·2015
    Same author

    An equilibrium and stability study of Δ(1)-pyrroline.

    Journal of chemical ecology·2013
    Same author

    NMR spectral assignment of lactone pheromone components emitted by Caribbean and Mexican fruit flies.

    Journal of chemical ecology·2013
    Same author

    The psychological wellbeing of patients following excision of a pilonidal sinus.

    Journal of wound care·2013
    Same journal

    Real-world Safety and Performance of the Symani Surgical System® in Microsurgical Reconstructive Procedures: Primary Results from the PRIMO Study.

    Annals of surgery·2026
    Same journal

    Revisiting Simultaneous Liver and Kidney Transplantation from Donors After Circulatory Death in the Era of Machine Perfusion Technologies: A US Nationwide Analysis of 10,687 Cases.

    Annals of surgery·2026
    Same journal

    The International Medical Graduate Paradox.

    Annals of surgery·2026
    Same journal

    Defining the Incremental Value of Endoscopic Ultrasound in Assessing Pancreatic Cystic Neoplasms.

    Annals of surgery·2026
    Same journal

    Trends in Metabolic and Bariatric Surgery and GLP-1 Receptor Agonist Use Among Adolescents with Severe Obesity.

    Annals of surgery·2026
    Same journal

    The Ambulatory Surgery Center Paradox: Why 60% of Surgeries Occur Where 2% of AI Research Happens.

    Annals of surgery·2026
    See all related articles

    Aortic saddle embolus (ASE) treatment is successful with high-dose heparin, embolectomy without preoperative angiography, and long-term anticoagulation. Early intervention within 6 hours did not significantly impact outcomes in this study.

    Area of Science:

    • Vascular Surgery
    • Cardiology
    • Thromboembolic Disease

    Background:

    • Aortic saddle embolus (ASE) is a rare condition affecting the aortic bifurcation.
    • Clinical experience with ASE is limited due to its infrequent occurrence.
    • Patients often present with bilateral lower extremity ischemia.

    Purpose of the Study:

    • To review clinical experience with ASE.
    • To identify diagnostic, anticoagulation, and operative features impacting treatment outcomes.
    • To evaluate the role of preoperative angiography and timing of surgery.

    Main Methods:

    • Retrospective review of 26 patients treated for ASE between 1962-1982.
    • Analysis of patient demographics, symptoms, diagnostic methods, surgical approaches, and outcomes.

    Related Experiment Videos

  • Evaluation of anticoagulation strategies, including heparin and Coumadin.

    • Main Results:

    • 96% of emboli were cardiac in origin; 1/3 occurred in patients with prior chronic ischemia.
    • Symptoms manifested >6 hours post-embolization, unlike distal emboli.
    • Surgery timing (<6 hours vs. >6 hours) did not significantly affect outcomes.
    • High-dose heparinization and long-term anticoagulation were associated with positive results.
    • Fogarty catheter embolectomy had a 14% mortality; direct aortic approach had 0% mortality.
    • Re-embolization occurred in 27% of patients, often linked to inadequate anticoagulation.

    Conclusions:

    • Successful ASE treatment relies on perioperative high-dose heparin, embolectomy without preoperative angiography, and long-term oral anticoagulation.
    • Early intervention within 6 hours is not a critical factor for ASE outcomes.
    • Maintaining adequate anticoagulation post-discharge is crucial to prevent re-embolization.